Hangzhou Leaflife Chemical Co., Ltd.

Products

 

CYPROCONAZOLE

 

Fungicide
FRAC  3; DMI: triazole

CYPROCONAZOLE

 

NOMENCLATURE
Common name cyproconazole (BSI, draft E-ISO, (m) draft F-ISO)
IUPAC name (2RS,3RS;2RS,3SR)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol 
Chemical Abstracts name a-(4-chlorophenyl)-a-(1-cyclopropylethyl)-1H-1,2,4-triazol-1-ethanol 
CAS RN [94361-06-5] for (2RS,3RS;2RS,3SR) isomers; [113096-99-4] for unstated stereochemistry; [94361-07-6] for (2RS,3SR) isomers  Development codes SAN 619 F (Sandoz) 

PHYSICAL CHEMISTRY
Composition It is a mixture (c. 1:1) of 2 diastereoisomers.  Mol. wt. 291.8  M.f. C15H18ClN3O  Form Colourless solid.  M.p. 106-109 ºC  B.p. >250 ºC  V.p. 3.46 ´ 10-2 mPa (20 ºC)  KOW logP = 2.91 (pH 7)  S.g./density 1.259 g/cm3  Solubility In water 140 mg/l (25 ºC). In acetone 230, ethanol 230, dimethyl sulfoxide 180, xylene 120 (all in g/l, 25 ºC).  Stability Decomposition is <5% after storage for 2 years. Stable in aqueous solutions at pH 1-9 for a test period of 35 days (50 ºC) or 14 days (80 ºC). Slowly hydrolysed in 1N HCl and NaOH.  pKa No acid or base properties in range pH 3.5-10.  F.p. No reaction up to 360 ºC 

COMMERCIALISATION
History Fungicide reported by U. Gisi et al. (Proc. Br. Crop Prot. Conf., 1986, 1, 33; 2, 857). Introduced in France and Switzerland (1989) by Sandoz AG (now Syngenta AG).  Patents US 4664696  Manufacturers Syngenta

APPLICATIONS

Biochemistry Steroid demethylation inhibitor.  Mode of action Systemic fungicide with protective, curative, and eradicant action. Absorbed rapidly by the plant, with translocation acropetally.  Uses Foliar, systemic fungicide for control of Septoria, rust, powdery mildew, Rhynchosporium, Cercospora, and Ramularia in cereals and sugar beet, at 60-100 g/ha; and rust, Mycena, Sclerotinia and Rhizoctonia in coffee and turf.  Formulation types SC; SL; WG.