Products

 

CLOFENTEZINE

 

Acaricide: tetrazine


NOMENCLATURE
Common name clofentezine (BSI, ANSI, draft E-ISO, (f) draft F-ISO)
IUPAC name 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine 
Chemical Abstracts name 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine 
Other names bisclofentezin* (rejected common name proposal)  CAS RN [74115-24-5]  EEC no. 277-728-2  Development codes NC 21 314 (Fisons) 

PHYSICAL CHEMISTRY
Mol. wt. 303.1  M.f. C14H8Cl2N4  Form Magenta crystals.  M.p. 182.3 ºC  V.p. 1.3 ´ 10-4 mPa (25 ºC) (gas saturation and glc)  KOW logP = 4.1 (25 ºC)  Henry 1.97 ´ 10-4 Pa m3 mol-1 (calc.)  S.g./density 1.51 (20 °C)  Solubility In water 2.5 mg/l (pH 5, 22 ºC). In dichloromethane 37, acetone 9.3, hexane 1, ethanol 0.5 (all in g/l, 25 ºC).  Stability The a.i. and formulated products are stable to light, heat and air; on hydrolysis (22 ºC), DT50 248 h (pH 5), 34 h (pH 7), 4 h (pH 9).  F.p. Low flammability 

COMMERCIALISATION
Patents EP 5912  Manufacturers Aventis

APPLICATIONS
Mode of action Specific acaricide with contact action, and long residual activity. Inhibits embryo development.  Uses Control of eggs and young motile stages (but not adults) of Panonychus ulmi and Tetranychus spp. on pome fruit and stone fruit (20 g/hl), citrus fruit (12.5-20 g/hl), nuts, vines (20 g/hl), hops, strawberries (200-300 g/ha), cucurbits (100-400 g/ha), cotton (150-250 g/ha), and ornamentals (20-30 g/hl). Has no effect on predatory mites or beneficial insect species.  Phytotoxicity May cause slight injury to glasshouse roses. May cause a slight pink deposit on petals of white or pale flowers.  Formulation types SC; WP.  Selected tradenames: 'Apollo' (Aventis)